BDBM50459511 CHEMBL4212332

SMILES Cc1cc2ccccc2n1CC(=O)OCC(=O)Nc1c(C)nn(c1C)-c1ccccc1

InChI Key InChIKey=CBUSMXLYARPCKI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50459511   

TargetCoagulation factor X(Homo sapiens (Human))
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459511(CHEMBL4212332)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of factor 10a (unknown origin) pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459511(CHEMBL4212332)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of thrombin (unknown origin) pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459511(CHEMBL4212332)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of trypsin (unknown origin) pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-6(Homo sapiens (Human))
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459511(CHEMBL4212332)
Affinity DataIC50:  640nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed