BDBM50459884 CHEMBL4228846

SMILES Brc1cccc2cc(sc12)C(=O)N[C@@H]1CCCNC1

InChI Key InChIKey=LRYYPTVUWGMZQB-SNVBAGLBSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50459884   

LigandPNGBDBM50459884(CHEMBL4228846)
Affinity DataEC50:  660nMAssay Description:Positive allosteric modulation of human alpha2beta2 nAChR expressed in HEK cells preincubated for 15 mins followed by dihydro-beta-erythroidine hydro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50459884(CHEMBL4228846)
Affinity DataEC50:  275nMAssay Description:Positive allosteric modulation of human (alpha4beta2)2beta2 nAChR expressed in HEK cells preincubated for 15 mins followed by dihydro-beta-erythroidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50459884(CHEMBL4228846)
Affinity DataEC50:  237nMAssay Description:Positive allosteric modulation of human alpha4beta4 nAChR expressed in HEK cells preincubated for 15 mins followed by dihydro-beta-erythroidine hydro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50459884(CHEMBL4228846)
Affinity DataEC50:  286nMAssay Description:Positive allosteric modulation of human alpha2beta4 nAChR expressed in HEK cells preincubated for 15 mins followed by dihydro-beta-erythroidine hydro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50459884(CHEMBL4228846)
Affinity DataEC50:  446nMAssay Description:Positive allosteric modulation of human alpha4beta2 nAChR expressed in HEK cells preincubated for 15 mins followed by dihydro-beta-erythroidine hydro...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed