BDBM50461449 CHEMBL4229058

SMILES CCOc1c2CN(C(=O)c2c(OCC)c2ccccc12)c1ccc(CC(O)=O)c(F)c1

InChI Key InChIKey=YJEFCZJZEASKIO-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50461449   

TargetThromboxane A2 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50461449(CHEMBL4229058)
Affinity DataIC50: <1.00E+4nMAssay Description:Activity at TP receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50461449(CHEMBL4229058)
Affinity DataEC50:  40nMAssay Description:Partial agonist activity at human EP4 receptor expressed in HEK293-AEQ17 cells assessed as cAMP accumulation by aequorin luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50461449(CHEMBL4229058)
Affinity DataIC50: <1.00E+4nMAssay Description:Activity at EP1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50461449(CHEMBL4229058)
Affinity DataIC50: <1.00E+4nMAssay Description:Activity at EP3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50461449(CHEMBL4229058)
Affinity DataIC50: <3.16E+4nMAssay Description:Activity at DP1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50461449(CHEMBL4229058)
Affinity DataIC50: <1.00E+4nMAssay Description:Activity at FP receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50461449(CHEMBL4229058)
Affinity DataEC50:  6.30nMAssay Description:Partial agonist activity at EP4 receptor in human whole blood assessed as inhibition of LPS-induced TNFalpha productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed