BDBM50463854 CHEMBL4251427
SMILES FC(F)(F)c1ccc(cc1)[C@H](NC(=O)c1ccc(=O)[nH]c1)c1ncccc1C(F)(F)F
InChI Key InChIKey=FHDVDXXLSCUTNI-INIZCTEOSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50463854
TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 mi...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Antagonist activity at mouse TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair