BDBM50463855 CHEMBL4248077

SMILES Fc1cccnc1[C@@H](NC(=O)c1ccc(=O)[nH]c1)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=IJTSMWHYNKDXNG-INIZCTEOSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463855   

TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
TBA

Curated by ChEMBL

LigandBDBM50463855(CHEMBL4248077)Copy SMILESCopy InChI

Affinity DataIC50:  15nMAssay Description:Antagonist activity at mouse TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50463855(CHEMBL4248077)Copy SMILESCopy InChI

Affinity DataIC50:  10nMAssay Description:Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTransient receptor potential cation channel subfamily M member 8(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

LigandBDBM50463855(CHEMBL4248077)Copy SMILESCopy InChI

Affinity DataIC50:  21nMAssay Description:Antagonist activity at rat TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 mi...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI