BDBM50463914 CHEMBL4241365

SMILES CSc1ccn2c3c(c(C(=O)NCCN(C)C)c2c1)C(=O)c1cccnc1C3=O

InChI Key InChIKey=LENCVJLQNLPRCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463914   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50463914(CHEMBL4241365)
Affinity DataIC50:  50nMAssay Description:Inhibition of IDO1 (unknown origin) assessed as reduction in N'-formlylkynurenine formation using D-Tryptophan as substrate in presence of aspartate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50463914(CHEMBL4241365)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of IFN-gamma-stimulated IDO1 in human HeLa cells after 24 hrs by Ehrlich's reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed