BDBM50464550 CHEMBL4294168::US10464907, Compound 21a::US10889552, Compound 21a
SMILES CNC(=O)c1ccc(CN(C)C(=O)c2cc(Cl)c(O)cc2O)cc1
InChI Key InChIKey=AQXXDVOEHJACGB-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50464550
Affinity DataIC50: 496nMAssay Description:Inhibition of FITC-geldanamycin binding to N-terminal domain of recombinant full-length HSP90alpha (unknown origin) after 16 hrs by fluorescence pola...More data for this Ligand-Target Pair
Affinity DataIC50: 496nMAssay Description:Endonuclease activity assays were carried out in Black Costar 96-well plates. Each well contained a total volume of 100 μL comprised of: buffer ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Bovine)
Industry Academic Cooperation Foundation Keimyung University
US Patent
Industry Academic Cooperation Foundation Keimyung University
US Patent
Affinity DataIC50: 496nMAssay Description:Fluorescence polarization assay was performed to confirm the binding ability to the compound synthesized with HSP90 according the concentration. 1 M ...More data for this Ligand-Target Pair