BDBM50465358 CHEMBL4284649::US10669276, Example 31
SMILES Cc1ncn(n1)-c1ccc(Nc2nc3N(CC(C)(C)c3c(NCCO)n2)c2ccc(F)cc2)cc1F
InChI Key InChIKey=VPWBOVDRCVZICM-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50465358
Affinity DataEC50: 15nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair