BDBM50465983 CHEMBL4277689

SMILES [H][C@]1(OC(=C[C@H](NC(N)=N)[C@H]1NC(=O)CCC(C)C)C(O)=O)[C@H](O)[C@H](O)CO

InChI Key InChIKey=CGSNXPGJUHSVOX-ZZEHVWSGSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50465983   

TargetSialidase-2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50465983(CHEMBL4277689)
Affinity DataKi:  1.30E+3nMAssay Description:Competitive inhibition of N-terminal MBP-fused human NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated with substrate for 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSialidase-1(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50465983(CHEMBL4277689)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human His6-tagged NEU1 expressed in HEK293 cells using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSialidase-3(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50465983(CHEMBL4277689)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of N-terminal MBP-fused human NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSialidase-4(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50465983(CHEMBL4277689)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of MBP-fused human NEU4 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSialidase-2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50465983(CHEMBL4277689)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of N-terminal MBP-fused human NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed