BDBM50466803 AMG-900::AMG900::Amg 900

SMILES Cc1csc(c1)-c1nnc(Nc2ccc(Oc3ncccc3-c3ccnc(N)n3)cc2)c2ccccc12

InChI Key InChIKey=IVUGFMLRJOCGAS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50466803   

TargetAurora kinase B(Homo sapiens (Human))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50466803(AMG-900 | AMG900 | Amg 900)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant aurora B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50466803(AMG-900 | AMG900 | Amg 900)
Affinity DataIC50:  5nMAssay Description:Inhibition of Aurora A kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase C(Homo sapiens (Human))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50466803(AMG-900 | AMG900 | Amg 900)
Affinity DataIC50:  1nMAssay Description:Inhibition of Aurora C kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed