BDBM50468112 CHEMBL4277404::US11247985, Table 3.63
SMILES CC(C)N1CCN(CC1)C1(CNC2CCN(CC2)c2cccc(c2)-c2cc3cc(F)ccc3[nH]2)COC1
InChI Key InChIKey=UTPLVVVRULZSDS-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50468112
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University of Pittsburgh
US Patent
University of Pittsburgh
US Patent
Affinity DataIC50: 41nMAssay Description:To optimize p97 inhibitors, the C-5 trifluoromethylated trifluoromethylated indole 12 was generated as a promising lead structure. In the ADP-Glo ass...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University of Pittsburgh
US Patent
University of Pittsburgh
US Patent
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...More data for this Ligand-Target Pair