BDBM50468115 CHEMBL4278176::US11247985, Table 3.117
SMILES CC(C)N1CCC(CC1)N[C@H]1CC[C@@H](CC1)c1cccc(c1)-c1cc2cc(F)ccc2[nH]1
InChI Key InChIKey=PILBHAWLGPGBMJ-WBANQOEISA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50468115
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University of Pittsburgh
US Patent
University of Pittsburgh
US Patent
Affinity DataIC50: 175nMAssay Description:To optimize p97 inhibitors, the C-5 trifluoromethylated trifluoromethylated indole 12 was generated as a promising lead structure. In the ADP-Glo ass...More data for this Ligand-Target Pair
TargetTransitional endoplasmic reticulum ATPase(Homo sapiens (Human))
University of Pittsburgh
US Patent
University of Pittsburgh
US Patent
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant full length human p97 (1 to 806 residues) expressed in Escherichia coli Rosetta 2 (DE3) using 100 uM ATP as substrate after...More data for this Ligand-Target Pair