BDBM50468394 CHEMBL4290147::US11834432, Compound S3

SMILES CNC(=O)c1cccc2cc(Oc3ccnc(NC(=O)c4ccc(OCC5(N)CC5)cc4)c3)ccc12

InChI Key InChIKey=XPEUYRKTSFCLBQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50468394   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50468394(CHEMBL4290147 | US11834432, Compound S3)
Affinity DataIC50: <10nMAssay Description:1. Enzyme reaction substrate μPoly(Glu,Tyr)4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM50468394(CHEMBL4290147 | US11834432, Compound S3)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA based spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed