BDBM50468411 CHEMBL4278402::US11834432, Compound S22

SMILES CNC(=O)c1cccc2cc(Oc3ccnc(NC(=O)c4ccc(NC(=O)C=C)cc4)c3)ccc12

InChI Key InChIKey=UPFCQMLUUMENSZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468411   

TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50468411(CHEMBL4278402 | US11834432, Compound S22)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant FGFR1 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA based spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50468411(CHEMBL4278402 | US11834432, Compound S22)
Affinity DataIC50: <100nMAssay Description:1. Enzyme reaction substrate μPoly(Glu,Tyr)4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50468411(CHEMBL4278402 | US11834432, Compound S22)
Affinity DataIC50: <100nMAssay Description:1. Enzyme reaction substrate μPoly(Glu,Tyr)4:1 was diluted with PBS without potassium ion (10 mM sodium phosphate buffer, 150 mM NaCl, pH7.2-7.4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent