BDBM50469204 CHEMBL4282601

SMILES CN1CCN(CCCNc2cc(ncn2)C2(CC2)C(=O)Nc2cc(ccc2C)C(=O)Nc2ccc(c(Cl)c2)C(F)(F)F)CC1

InChI Key InChIKey=GZCIDSUBIQFYQY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469204   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50469204(CHEMBL4282601)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase A-Raf(Homo sapiens (Human))
University Of Science & Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50469204(CHEMBL4282601)
Affinity DataIC50:  25nMAssay Description:Inhibition of ARAF (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Science & Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50469204(CHEMBL4282601)
Affinity DataIC50:  13nMAssay Description:Inhibition of CRAF (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
University Of Science & Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50469204(CHEMBL4282601)
Affinity DataIC50:  30nMAssay Description:Inhibition of BRAF (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed