BDBM50469376 CHEMBL4284541

SMILES CCCCNc1ncc2c(cn([C@H]3CC[C@H](O)CC3)c2n1)-c1ccc(cc1)C1(CC1)N1CCN(C)CC1

InChI Key InChIKey=RGJASBGADDXMBE-SOAUALDESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469376   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Unc Eshelman School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469376(CHEMBL4284541)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of FLT3 (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))
Unc Eshelman School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469376(CHEMBL4284541)
Affinity DataIC50:  27nMAssay Description:Inhibition of TYRO3 (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))
Unc Eshelman School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469376(CHEMBL4284541)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MERTK (unknown origin) using 5'-FAM-EFPIYDFLPAKKK-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Unc Eshelman School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50469376(CHEMBL4284541)
Affinity DataIC50:  15nMAssay Description:Inhibition of AXL (unknown origin) using 5'-FAM-KKKKEEIYFFF-CONH2 as substrate after 180 mins by MCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed