BDBM50470568 CHEMBL4293438
SMILES Nc1ccccc1NC(=O)CCCCCCC(=O)Nc1ccc(cc1)-c1cn(Cc2ccccc2)nn1
InChI Key InChIKey=IYKIQDXPWYJSPM-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50470568
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Jadavpur University
Curated by ChEMBL
Jadavpur University
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of His6-tagged HDAC3/SMRT (395 to 489 residues) (unknown origin) co-expressed in baculovirus infected sf9 cells using (FAM)-labeled acetyl...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute
Curated by ChEMBL
Indian Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute
Curated by ChEMBL
Indian Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HDAC2 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute
Curated by ChEMBL
Indian Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute
Curated by ChEMBL
Indian Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HDAC10 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Indian Csir-Central Drug Research Institute
Curated by ChEMBL
Indian Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of HDAC8 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of HDAC3 (unknown origin) using (FAM)-labeled acetylated peptide as substrate measured after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair