BDBM50470576 CHEMBL4294949

SMILES Nc1ccccc1NC(=O)c1ccc(CN2CC(=C)c3ccccc3C2=O)cc1

InChI Key InChIKey=GTLTXEIKQVWSRF-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50470576   

TargetHistone deacetylase 3(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50:  16nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50:  220nMAssay Description:Inhibition of HDAC3 (unknown origin) using peptide substrate measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant human HDAC4 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC6 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of human recombinant HDAC3 at 0.5 uM using Fluor-de-Lys substrate incubated for 30 mins by fluorometric activity assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant human HDAC2 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human HDAC8 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of recombinant human HDAC7 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of recombinant human HDAC1 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50470576(CHEMBL4294949)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human HDAC3 using fluorescently-labeled acetylated histone peptide as substrate by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed