BDBM50474249 CHEMBL106158
SMILES C\N=C(\NC[C@@H]1CC[C@@H](O1)c1c[nH]cn1)NC#N
InChI Key InChIKey=CCOQWVUQXNRKKP-WCBMZHEXSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50474249
Affinity DataKi: 200nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair
Affinity DataKi: 224nMAssay Description:Histamine H4 receptor competition binding using [3H]Na-methylhistamineMore data for this Ligand-Target Pair
Affinity DataKi: 6.31E+3nMAssay Description:Displacement of [3H]Nalpha-methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.08E+3nMAssay Description:Histamine H3 receptor competition binding using [3H]Na-methylhistamineMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Agonist activity at human histamine H4 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Agonist activity at human histamine H3 receptor expressed in human SK-N-MC cells by CRE-beta galactosidase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 224nMAssay Description:Inhibition of the forskolin-stimulated cAMP production in SK-N-MC cells expressing human Histamine H4 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.02E+4nMAssay Description:Inhibition of the forskolin-stimulated cAMP production in SK-N-MC cells expressing human Histamine H3 receptorMore data for this Ligand-Target Pair