BDBM50477683 CHEMBL250820
SMILES COc1ccc(CN([C@@H]2CCCCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)cc1F
InChI Key InChIKey=HHLUAUWJQNAVGJ-GOSISDBHSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50477683
Affinity DataIC50: 170nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 9.10nMAssay Description:Inhibition of gamma-secretase assessed as reduction of amyloid-beta 40 levels in H4 cellsMore data for this Ligand-Target Pair