BDBM50478063 CHEMBL256794

SMILES COc1ccc(CN([C@@H]2CC(F)(F)CCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)cn1

InChI Key InChIKey=NBXQCRIMLNZIEK-MRXNPFEDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50478063   

TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50478063(CHEMBL256794)
Affinity DataIC50:  30nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed