BDBM50478072 CHEMBL256854

SMILES Clc1ccc(cc1)S(=O)(=O)N(Cc1ccc2OCOc2c1)C1CCCCNC1=O

InChI Key InChIKey=BABVQHAUMWGULB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50478072   

TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50478072(CHEMBL256854)
Affinity DataIC50:  400nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed