BDBM50478727 CHEMBL490267::TX-2037

SMILES [#6]C([#6])([#6])c1ccc(-[#8]-[#6]-[#6@H](-[#6]-n2ccnc2-[#7+](-[#8-])=O)-[#8]-[#6](=O)-c2ccc(-[#7]\[#6]=[#6]-3/[#6](=O)-[#6]=[#6]-[#6]-3=O)cc2)cc1

InChI Key InChIKey=NUMKSDJRUKJUOU-QHCPKHFHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50478727   

Target72 kDa type IV collagenase(Homo sapiens (Human))
The University Of Tokushima

Curated by ChEMBL
LigandPNGBDBM50478727(CHEMBL490267 | TX-2037)
Affinity DataIC50:  1.83E+5nMAssay Description:Inhibition of human bowes melanoma cell MMP2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Bos taurus)
The University Of Tokushima

Curated by ChEMBL
LigandPNGBDBM50478727(CHEMBL490267 | TX-2037)
Affinity DataIC50:  1.03E+5nMAssay Description:Inhibition of bovine arterial endothelial cell MMP9More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
The University Of Tokushima

Curated by ChEMBL
LigandPNGBDBM50478727(CHEMBL490267 | TX-2037)
Affinity DataIC50:  1.84E+4nMAssay Description:Inhibition of human A431 cell EGFRK assessed as 32P phosphorylation by scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
The University Of Tokushima

Curated by ChEMBL
LigandPNGBDBM50478727(CHEMBL490267 | TX-2037)
Affinity DataIC50:  1.84E+5nMAssay Description:Inhibition of Flt1 expressed in mouse NIH3T3 cells by autoradiographyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed