BDBM50479142 Guineensine::Guineesine::Pipyahyine

SMILES CC(C)CNC(=O)\C=C\C=C\CCCCCC\C=C\c1ccc2OCOc2c1

InChI Key InChIKey=FPMPOFBEYSSYDQ-AUVZEZIHSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50479142   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50479142(Guineensine | Guineesine | Pipyahyine)
Affinity DataKi: >2.00E+4nMAssay Description:Displacement of [3H]-CP55940 from recombinant human CB1 receptor measured after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50479142(Guineensine | Guineesine | Pipyahyine)
Affinity DataKi:  3.83E+4nMAssay Description:Displacement of [3H]-CP55940 from recombinant human CB2 receptor measured after 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid-binding protein 5(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50479142(Guineensine | Guineesine | Pipyahyine)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of NBD-Stearate from recombinant human FABP5 measured after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50479142(Guineensine | Guineesine | Pipyahyine)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of MAGL in human U937 cell homogenates using [3H]-2OG as substrate preincubated for 15 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50479142(Guineensine | Guineesine | Pipyahyine)
Affinity DataIC50: >1.30E+5nMAssay Description:Inhibition of sICAM1/LFA1 interaction-mediated human THP1 cell adhesion after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Concordia University Wisconsin

Curated by ChEMBL
LigandPNGBDBM50479142(Guineensine | Guineesine | Pipyahyine)
Affinity DataIC50:  4.68E+4nMAssay Description:Inhibition of FAAH in human U937 cell homogenates using [14C]-AEA as substrate preincubated for 15 mins followed by substrate addition and measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed