BDBM50482776 CHEBI:70718::Ceftaroline Fosamil::PPI-0903::TAK-599
SMILES [H][C@]12SCC(Sc3nc(cs3)-c3cc[n+](C)cc3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OCC)\c1nsc(NP(O)(O)=O)n1)C([O-])=O
InChI Key InChIKey=ZCCUWMICIWSJIX-NQJJCJBVSA-N
Data 22 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50482776
TargetPutative penicillin-binding protein 2B(Staphylococcus aureus)
University Of Notre Dame
Curated by ChEMBL
University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 146nMAssay Description:Binding affinity to methicillin-susceptible Staphylococcus aureus PBP 1More data for this Ligand-Target Pair
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.46E+3nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 24 PBP2X by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.46E+3nMAssay Description:Binding affinity to methicillin-susceptible Staphylococcus aureus PBP 4More data for this Ligand-Target Pair
TargetPenicillin-binding protein, transpeptidase domain protein(Staphylococcus aureus)
University Of Notre Dame
Curated by ChEMBL
University Of Notre Dame
Curated by ChEMBL
Affinity DataIC50: 71.6nMAssay Description:Binding affinity to methicillin-susceptible Staphylococcus aureus PBP 3More data for this Ligand-Target Pair
Affinity DataIC50: 233nMAssay Description:Inhibition of methicillin-resistant Staphylococcus aureus PBP 2aMore data for this Ligand-Target Pair
Affinity DataIC50: 365nMAssay Description:Binding affinity to methicillin-, vancomycin-resistant, beta-lactamase-positive Staphylococcus aureus 510 PBP2a by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.46E+3nMAssay Description:Binding affinity to methicillin-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 1287 PBP2a by competitive binding a...More data for this Ligand-Target Pair
Affinity DataIC50: 14.6nMAssay Description:Binding affinity to against methicillin-, daptomycin-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 25 PBP2a by co...More data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 182nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 24 PBP1A by competitive binding assayMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 365nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 3413 PBP1A by competitive binding assayMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 365nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 3413 PBP2X by competitive binding assayMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 24 PBP2B by competitive binding assayMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 146nMAssay Description:Binding affinity to against penicillin-susceptible Streptococcus pneumoniae 1076 PBP2X by competitive binding assayMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 5.84E+3nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 2527 PBP2B by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Binding affinity to methicillin-resistant, heteroresistant vancomycin-intermediate, beta-lactamase-negative Staphylococcus aureus 873 PBP2a by compet...More data for this Ligand-Target Pair
Affinity DataIC50: 1.46E+3nMAssay Description:Binding affinity to methicillin-, linezolid-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 2149A PBP2a by competit...More data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 365nMAssay Description:Binding affinity to against penicillin-susceptible Streptococcus pneumoniae 1076 PBP1A by competitive binding assayMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 365nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 2527 PBP1A by competitive binding assayMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 2.92E+3nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 3413 PBP2B by competitive binding assayMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 5.84E+3nMAssay Description:Binding affinity to against penicillin-susceptible Streptococcus pneumoniae 1076 PBP2B by competitive binding assayMore data for this Ligand-Target Pair
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Hershey Medical Center
Curated by ChEMBL
Hershey Medical Center
Curated by ChEMBL
Affinity DataIC50: 146nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 2527 PBP2X by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 49.7nMAssay Description:Binding affinity to methicillin-susceptible Staphylococcus aureus PBP 2More data for this Ligand-Target Pair