BDBM50484976 CHEMBL2017496

SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCCCCNC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](C[C@@H](O)[C@H](Cc3ccccc3)NC(=O)c3ccc(cc3)C(=O)c3ccccc3)Cc3ccccc3)[C@@]1([H])NC(=O)N2

InChI Key InChIKey=ZMFNTPVSIPZVIG-DJYVFMJFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484976   

TargetPresenilin-1(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50484976(CHEMBL2017496)
Affinity DataIC50:  817nMAssay Description:Inhibition of gamma-secretase in cell-free human HeLa membrane assessed as amyloid beta-42 production using APP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed