BDBM50485974 CHEMBL2180376
SMILES COc1cc(\C=C2/CCCN3[C@H](CON=C23)c2ccc(F)cc2)ccc1-n1cnc(C)c1
InChI Key InChIKey=IQTCDSQBHHTVBN-GAISBVLPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50485974
Affinity DataIC50: 33nMAssay Description:Modulation of gamma secretase in HEK293 cells transfected with human APP with Swedish and London familial AD mutation assessed as reduction in Abeta4...More data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Modulation of gamma-secretase expressed in HEK293 cells co-expressing APPsw-lon assessed as reduction of amyloid-beta-42 level by sandwich immunoassa...More data for this Ligand-Target Pair