BDBM50490895 CHEMBL2347711

SMILES CCNC(=O)Nc1nc2ccc(cc2s1)-c1ccccc1OCC

InChI Key InChIKey=WIVSFJKYGWJWQH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50490895   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50490895(CHEMBL2347711)
Affinity DataIC50:  0.0640nMAssay Description:Inhibition of breakpoint cluster region-Abelson tyrosine kinase T315I mutant (unknown origin) using [gamma-33P]ATP as substrate by radiometric kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50490895(CHEMBL2347711)
Affinity DataIC50:  0.0640nMAssay Description:Inhibition of Abl T315I mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50490895(CHEMBL2347711)
Affinity DataIC50:  0.0300nMAssay Description:Inhibition of wild type Abl (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed