BDBM50490918 CHEMBL2347710
SMILES CCNC(=O)Nc1nc2ccc(cc2s1)-c1ccccc1OC
InChI Key InChIKey=LGPZTQXZPZVKSU-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50490918
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Inhibition of breakpoint cluster region-Abelson tyrosine kinase T315I mutant (unknown origin) using [gamma-33P]ATP as substrate by radiometric kinase...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of wild type Abl (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of Abl T315I mutant in mouse BaF3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of wild type Abl in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Korea Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Korea Institute Of Science And Technology (Kaist)
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Inhibition of Abl T315I mutant (unknown origin)More data for this Ligand-Target Pair