BDBM50491627 CHEMBL2386145

SMILES CC(C)(C)c1ccc(cc1)-c1ccc(cn1)C#N

InChI Key InChIKey=AWPJMIQUTCBORO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50491627   

TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50491627(CHEMBL2386145)
Affinity DataIC50: >5.00E+4nMAssay Description:Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed