BDBM50496205 CHEMBL3125043

SMILES COc1cc(Oc2ccc(cc2C=C)[C@H](NC(=O)[C@@H](NC(=O)OC(C)(C)C)C(C)(C)C)C(=O)Nc2cccc(c2)C(=O)NS(=O)(=O)c2ccc(cc2)C(F)(F)F)nc(n1)-c1ccccc1

InChI Key InChIKey=JRYMIUUGCMGFQZ-QPPIDDCLSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50496205   

TargetGenome polyprotein(Hepacivirus C)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50496205(CHEMBL3125043)
Affinity DataKi:  53nMAssay Description:Inhibition of Hepatitis C virus genotype 1a full length NS3/2K-NS4A protease A156T mutant using Ac-DED(Edans)EEAbupsi[COO]ASK(Dabcyl)-NH2 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepacivirus C)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50496205(CHEMBL3125043)
Affinity DataKi:  110nMAssay Description:Inhibition of Hepatitis C virus genotype 1a full length NS3/2K-NS4A protease D168V mutant using Ac-DED(Edans)EEAbupsi[COO]ASK(Dabcyl)-NH2 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepacivirus C)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50496205(CHEMBL3125043)
Affinity DataKi:  210nMAssay Description:Inhibition of Hepatitis C virus genotype 1a full length NS3/2K-NS4A protease R155K mutant using Ac-DED(Edans)EEAbupsi[COO]ASK(Dabcyl)-NH2 as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed