BDBM50498452 CHEMBL3596873
SMILES CC(C)(C)c1cc(NC(=O)Nc2cccc(Oc3cncc(n3)-c3ccc(cc3)S(C)(=O)=O)c2)no1
InChI Key InChIKey=MAGVRNDWTTZRHB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50498452
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of RET (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of KDR (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair