BDBM50498457 CHEMBL3596893
SMILES Cn1cc(cn1)-c1cncc(n1)-c1ccc(NC(=O)Nc2cc(nn2C)C(C)(C)C)cc1
InChI Key InChIKey=NIFOBCJOHDKDIO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50498457
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Inhibition of KDR (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona
Curated by ChEMBL
The University Of Arizona
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of RET (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair