BDBM50498458 CHEMBL3596868

SMILES CC(C)(C)c1cc(NC(=O)Nc2cccc(Oc3cncc(n3)-c3ccsc3)c2)no1

InChI Key InChIKey=SOLRFWOVULTERW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50498458   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50498458(CHEMBL3596868)
Affinity DataIC50:  120nMAssay Description:Inhibition of RET (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50498458(CHEMBL3596868)
Affinity DataIC50:  39nMAssay Description:Inhibition of human recombinant TrkA using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50498458(CHEMBL3596868)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of KDR (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50498458(CHEMBL3596868)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of EphB2 (unknown origin) using ATP and 5FAM tagged TrkA peptide substrate incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed