BDBM50499195 CHEMBL3735504

SMILES CC(C)(C)C(=O)Nc1ccc2n([C@@H]3CC[C@H](CO)CC3)c(NC(=O)c3cccc(c3)C(F)(F)F)nc2c1

InChI Key InChIKey=KBRPQKGSDUPEBR-MOBUCQHHSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499195   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50499195(CHEMBL3735504)
Affinity DataKi:  0.340nMAssay Description:Inhibition of recombinant full length IRAK-4 (unknown origin) using the biotinylated substrate RRRVTSPARRS by chemiluminescent ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50499195(CHEMBL3735504)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed