BDBM50499226 CHEMBL3734885

SMILES CC1(CCOCC1)n1nnc2CC(CCc12)c1nc(no1)-c1ccc(F)cc1

InChI Key InChIKey=GFLFKGVFLRGCNV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50499226   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Eisai

Curated by ChEMBL
LigandPNGBDBM50499226(CHEMBL3734885)
Affinity DataEC50:  10nMAssay Description:Positive allosteric modification of human recombinant mGlu5 receptor expressed in U2OS cells assessed as potentiation of glutamate-induced Ca2+ flux ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed