BDBM50499832 CHEMBL3740950

SMILES C[C@H]1N(CCn2c1nnc2C(F)(F)F)C(=O)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1

InChI Key InChIKey=ABVDCRPDOUVOTD-CYBMUJFWSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50499832   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50499832(CHEMBL3740950)
Affinity DataEC50: >1.10E+4nMAssay Description:Inhibition of PARP in human HeLa cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed