BDBM50499837 CHEMBL3740510

SMILES CC(C)c1nnc2CN([C@@H](C)Cn12)C(=O)c1cccc(c1)C(F)(F)c1n[nH]c(=O)c2ccccc12

InChI Key InChIKey=YXXLWOCQYWVSHE-HNNXBMFYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50499837   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50499837(CHEMBL3740510)
Affinity DataEC50:  102nMAssay Description:Inhibition of PARP in human HeLa cells assessed as induction of centrosome declustering after 48 hrs by DAPI-staining based image analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed