BDBM50500480 CHEMBL3747546

SMILES [H][C@@]12CN(C[C@]1([H])[C@H]2C(=O)OCC)C(=O)c1ccc(C[C@@H]2CC[C@@]([H])(N2)[C@H](O)c2ccccc2)cc1

InChI Key InChIKey=SDPATRJYTSCCAP-NCIBGLJCSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50500480   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50500480(CHEMBL3747546)
Affinity DataIC50:  1.34E+4nMAssay Description:Displacement of [125I]CYP from human beta-2 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50500480(CHEMBL3747546)
Affinity DataIC50: >2.00E+4nMAssay Description:Displacement of [125I]CYP from human beta-1 adrenergic receptor expressed in CHO cell membrane after 1 hr by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50500480(CHEMBL3747546)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human ERG by IKr binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck And

Curated by ChEMBL
LigandPNGBDBM50500480(CHEMBL3747546)
Affinity DataEC50:  0.490nMAssay Description:Agonist activity at human beta-3 adrenergic receptor expressed in CHO cells assessed as reduction in cAMP level after 30 mins by LANCE TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed