BDBM50502602 CHEMBL4557890
SMILES C[C@]1(Cn2cncc2C(N)=N1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F
InChI Key InChIKey=OBLWDHIBZWAGSY-FQEVSTJZSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50502602
TargetPotassium voltage-gated channel subfamily H member 1(Homo sapiens)
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of BACE1 in human SKNBE2 cells expressing wild type amyloid precursor protein (APP695) assessed as amyloid beta42 level incubated for 18 h...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair