BDBM50503099 CHEMBL4545269
SMILES Cc1cc(NC(=O)c2nn(C3CCN(CC3)C(=O)CC(C)(C)C#N)c3ccccc23)ccc1NC(=O)c1cnn2ccccc12
InChI Key InChIKey=NQWJYXLLLYRYCZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50503099
Affinity DataIC50: 4nMAssay Description:Inhibition of CSK (unknown origin) using fluorescent labeled peptide as substrate in presence of ATP at Km concentration by caliper methodMore data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of His-tagged/GST-tagged CSK (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: 88nMAssay Description:Effect on ZAP70 phosphorylation in human Jurkat cells pre-incubated for 30 mins followed by anti-CD3/CD28 stimulation measured after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of His-tagged/GST-tagged LCK (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair