BDBM50503349 CHEMBL4476817

SMILES NC(=N)Nc1cc(cc(c1)C(F)(F)F)C1CCNCC1

InChI Key InChIKey=SVJLJEMEWHBCNB-UHFFFAOYSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503349   

TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope

Curated by ChEMBL
LigandPNGBDBM50503349(CHEMBL4476817)
Affinity DataKd:  3.80E+4nMAssay Description:Binding affinity to human 15N-labeled STEP PTP domain (281 to 563 residues) expressed in Escherichia coli OD2 by 1H,15N TROSY NMR spectral analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein phosphatase non-receptor type 5(Homo sapiens (Human))
Beckman Research Institute Of The City Of Hope

Curated by ChEMBL
LigandPNGBDBM50503349(CHEMBL4476817)
Affinity DataKd:  8.00E+5nMAssay Description:Binding affinity to human STEP PTP domain (281 to 563 residues) expressed in Escherichia coli BL21(DE3) by ITCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB