BDBM50503435 CHEMBL4465797::US11274074, Comparative Example 2 [Chemical Formula 20]

SMILES COc1ccccc1-c1nnc(o1)-c1cc2cc(Cl)ccc2o1

InChI Key InChIKey=OWWZONVQAHWLHJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50503435   

TargetAnoctamin-2(Homo sapiens)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50503435(CHEMBL4465797 | US11274074, Comparative Example 2 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAnoctamin-2(Homo sapiens)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50503435(CHEMBL4465797 | US11274074, Comparative Example 2 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent
LigandPNGBDBM50503435(CHEMBL4465797 | US11274074, Comparative Example 2 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent
LigandPNGBDBM50503435(CHEMBL4465797 | US11274074, Comparative Example 2 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed