BDBM50503452 CHEMBL4459865::US11274074, Comparative Example 18 [Chemical Formula 36]

SMILES Cc1cc(Cl)ccc1OC(C)(C)C(=O)N\N=C\c1ccccc1OC(F)(F)F

InChI Key InChIKey=OVVMKQMYSFIIJK-BHGWPJFGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503452   

TargetAnoctamin-2(Homo sapiens)
Industry-Academic Cooperation Foundation Yonsei University

US Patent
LigandPNGBDBM50503452(CHEMBL4459865 | US11274074, Comparative Example 18...)
Affinity DataIC50: >1.00E+5nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAnoctamin-2(Homo sapiens)
Industry-Academic Cooperation Foundation Yonsei University

US Patent
LigandPNGBDBM50503452(CHEMBL4459865 | US11274074, Comparative Example 18...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of YFP-fused ANO2 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed