BDBM50503455 CHEMBL4448175::US11274074, Example 5 [Chemical Formula 9]

SMILES Cc1cc(Cl)ccc1OCC(=O)N\N=C\c1ccccc1C(F)(F)F

InChI Key InChIKey=NTVFFXVWKJPSMH-LSFURLLWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503455   

TargetAnoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent
LigandPNGBDBM50503455(CHEMBL4448175 | US11274074, Example 5 [Chemical Fo...)
Affinity DataIC50:  210nMAssay Description:The method for inhibiting the expression of ANO1 (TMEM16A) of the present disclosure includes a step of inhibiting the expression of ANO1 (TMEM16A) i...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAnoctamin-1(Homo sapiens (Human))
Industry-Academic Cooperation Foundation Yonsei University

US Patent
LigandPNGBDBM50503455(CHEMBL4448175 | US11274074, Example 5 [Chemical Fo...)
Affinity DataIC50:  210nMAssay Description:Inhibition of YFP-fused ANO1 (unknown origin) expressed in FRT cells after 20 mins by fluorescence quenching methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed