BDBM50503710 CHEMBL4475584

SMILES CN(Cc1cnc2ccccn12)C(=O)c1cc(COc2ccc3OCOc3c2)[nH]n1

InChI Key InChIKey=NHYXEHRLFDHBCG-UHFFFAOYSA-N

Data  4 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50503710   

Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503710(CHEMBL4475584)
Affinity DataEC50:  500nMAssay Description:Inhibition of PDK1 (unknown origin) using PDH E1 as substrate measured after 30 mins by kinase-glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503710(CHEMBL4475584)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK1 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503710(CHEMBL4475584)
Affinity DataKd:  2.60E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK4 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503710(CHEMBL4475584)
Affinity DataKd:  4.70E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK3 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial(Homo sapiens (Human))
Shaanxi Province Tuberculosis Prevention And Treatment Institute

Curated by ChEMBL
LigandPNGBDBM50503710(CHEMBL4475584)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to SUMO-fused/His-tagged PDK2 (unknown origin) expressed in Escherichia coli by isothermal calorimetric titration analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed