BDBM50503744 CHEMBL4563026
SMILES [#6]C1([#6])[#6]-[#6](-[#6]C([#6])([#6])[#7]1-[#8;v1])-[#7]-[#6](=O)-c1ccc(-[#7]-c2ncc(F)c(-[#7]-c3ccc(cc3)-[#6](=O)-[#7]-c3ccccc3Cl)n2)cc1
InChI Key InChIKey=SLYMRFHIVVKAEL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50503744
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of Aurora A (unknown origin) using kemptide acetate salt as substrate after 30 mins by kinase-Glo luminescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of Aurora B (unknown origin) using kemptide acetate salt as substrate after 30 mins by kinase-Glo luminescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 538nMAssay Description:Inhibition of Aurora B phosphorylation at Thr232 residue in human HeLa cells after 12 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Aurora A phosphorylation at Thr288 residue in human HeLa cells after 12 hrs by ELISAMore data for this Ligand-Target Pair