BDBM50504642 CHEMBL4592358

SMILES CC(C)C\C=N\c1c(C#N)c2CCCn2c1C(=O)Nc1ccc(Br)cc1

InChI Key InChIKey=PHKLPPLFTQEZFS-AUEPDCJTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50504642   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50504642(CHEMBL4592358)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human COX1 using arachidonic acid as substrate incubated for 2 mins by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50504642(CHEMBL4592358)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate incubated for 2 mins by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Umm Al-Qura University

Curated by ChEMBL
LigandPNGBDBM50504642(CHEMBL4592358)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of CDK2 (unknown origin) incubated for 40 mins by ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed