BDBM50505007 CHEMBL4464037

SMILES Cc1cc(ccc1Oc1ccccc1)-n1c(=O)[nH]c(=O)n(-c2ccccc2)c1=O

InChI Key InChIKey=REYFGVMCUDWCML-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50505007   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50505007(CHEMBL4464037)
Affinity DataEC50:  250nMAssay Description:Agonist activity at IGF1R (unknown origin) in expressed in HEK293 cells incubated for 3 hrs and measured after 60 hrs in presence of IGF-1 by fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50505007(CHEMBL4464037)
Affinity DataEC50:  340nMAssay Description:Agonist activity at TrkA (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of NGF by fluorescence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50505007(CHEMBL4464037)
Affinity DataEC50:  390nMAssay Description:Agonist activity at TrkB (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of BDNF by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50505007(CHEMBL4464037)
Affinity DataEC50:  290nMAssay Description:Agonist activity at FGFR1 (unknown origin) in expressed in U2OS cells incubated for 3 hrs and measured after 60 hrs in presence of (bFGF(FGF-2))by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed