BDBM50505137 CHEMBL4457441

SMILES Fc1cc(F)cc(c1)N1CCN(CC1)C(=O)C(=O)Nc1ccc2[nH]c(=O)oc2c1

InChI Key InChIKey=QUPZOMBCZNJPOR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505137   

TargetGlutamate receptor ionotropic, NMDA 2B(Mus musculus)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50505137(CHEMBL4457441)
Affinity DataIC50:  100nMAssay Description:Antagonist activity at mouse NR2B receptor expressed in HEK293 cells co-expressing NR1 subunit assessed as reduction in glutamic acid/glycine-induced...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50505137(CHEMBL4457441)
Affinity DataIC50:  158nMAssay Description:Displacement of [3H]-ifenprodil from NR2B receptor in rat brain cerebral cortex membranes incubated for 120 mins by liquid scintillation counting met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed